There's a few ways to accomplish this:
ng-if
<span>
Delete <strong ng-if="vm.name">vm.name</strong><span ng-if="!vm.name">this user</span>?
</span>
This will show <strong ng-if="vm.name">vm.name</strong> if vm.name exists, and <span ng-if="!vm.name">this user</span> if they do not.
conditional classes
<style>
.bold {
font-weight: bold;
}
</style>
<span>
Delete <span ng-class="{bold: vm.name}">{{ vm.name ? vm.name : 'this user'}}</span>?
</span>
This will conditionally add the class bold to your span. You need to add your own CSS to that class (unless it exists already).
There's also something you can do with ng-bind-html, but it's a bit of a pain and I wouldn't recommend it.
<strong>tag<strong>tag, yes.