How to call a javascript function in a js file inside jade file

I have a two files called sample.jade and another file called insertToEnrolledSubjects.js file,(and I'm using nodejs with express framework and for db i'm using mongo db)

sample.jade file displays a table with course details. By clicking Enroll, edit ,delete button in each row of the table students can enroll for courses,edit course or delete it. So there when i click Enroll button it shows a pop up message asking about confirmation when user clicks "ok" button i need to call "insertToEnrolledSubjects" function in insertToEnrolledSubjects.js file how can i do that? Please can anyone give me a better solution i tried a lot but i didn't get any result.

sample.jade



 html
    head
        title="Enroll For Subjects"
        link(rel='stylesheet', href='/bootstrap/css/bootstrap.min.css')
        link(rel='stylesheet', href='/bootstrap/css/bootstrap-responsive.min.css')


    script(src='https://ajax.googleapis.com/ajax/libs/jquery/1/jquery.min.js')
            script(src='bootstrap/js/bootstrap.min.js')
            script(src="insertToEnrolledSubjects.js")
        body
            div.container
                div.content
                    h2.display-4.m-b-2 Course criteria 
                    table.table.table(border='2')
                        thead
                            tr
                                th Course ID
                                th Subject name
                                th Year
                                th Credits
                                th Action
                        tbody
                            - for (var i = 1; i <= 5; ++i){ 
                            tr
                                    td=i
                                    td="IPE"
                                    td=i
                                    td=5
                                    td
                                            button.btn.btn-danger(type='submit',onclick='Enroll("#{i}")') Enroll
                                    td
                                            button.btn.btn-danger(type='submit',onclick='Edit("#{i}")') Edit
                                    td
                                            button.btn.btn-danger(type='submit',onclick='delete1("#{i}")') Delete
                            - }

            script.
                function delete1(d){
                    var val = confirm("Do you want to delete this record?");
                    if(val == true){
                        window.location.href= '/delete1/'+d;
                        return true;
                    }
                    else{
                        return false;
                    }
                    };

            script.
                function Enroll(d){
                    var val = confirm("Do you really want to enroll for this course?");
                    if(val == true){
                        val2 = confirm("came");
                        insertToEnrolledSubjects(d,1);
                        val3 = confirm("came3");
                        }};




    insertToEnrolledSubjects.js
    var MongoClient = require('mongodb').MongoClient
        , format = require('util').format;
        MongoClient.connect("mongodb://localhost:27017/test", function (err, db) {

        if (err) 
            throw err;
        else {
            console.log("successfully connected to the database!!!");

             //calling insert function
            insertToEnrolledSubjects(cid,e);

            //implementation of insert function
            function insertToEnrolledSubjects(courseid,enrolled) {
            db.collection('EnrolledSubjects').insert({ courseId:courseid ,NoOfEnrolledStudents:enrolled});

            console.log("Inserted!");

            //Show total no of reults in db
            db.collection('EnrolledSubjects').count(function (err, count) {
                if (err) throw err;

                console.log("Total Rows: " + count);
            });
            }


        }});