As already commented, creating a prefab with one or multiple child objects works without any modification. But keep in mind - if you delete one or many child(s) it will break the instantiated prefab's connection to the prefab. Once the connection is broken, changing the prefab will not apply to the instantiated prefabs.

As already commented, creating a prefab with one or multiple child objects works without any modification. But keep in mind - if you delete one or many child(ren) it will break the instantiated prefab's connection to the prefab. Once the connection is broken, changing the prefab will not apply to the instantiated prefabs.