I'm not very familiar with Wordpress' pagination so I'm not sure if this a stupid question.
Layout:

Code:
<?php
/**
* Template Name: Pictures Page
* @package WordPress
* @subpackage Prominent
* @since Prominent 1.0
*/
get_header(); ?>
<div id="tagline">
<div class="container">
<?php // Run main loop (The Loop). ?>
<?php if ( have_posts() ) while ( have_posts() ) : the_post(); ?>
<div class="content0">
<?php the_content(); ?>
</div>
<?php endwhile; ?>
</div><!-- .container -->
</div><!-- #content-bottom -->
<div id="content">
<div class="container">
<div id="mainbar">
<?php $custom_posts = new WP_Query(); ?>
<?php $custom_posts->query('category_name=Pictures'); ?>
<?php while ($custom_posts->have_posts()) : $custom_posts->the_post(); ?>
<div class="content-block-2">
<a href="<?php the_permalink(); ?>" title="<?php printf( esc_attr__( 'Permalink to %s', 'twentyten' ), the_title_attribute( 'echo=0' ) ); ?>" rel="bookmark"><?php the_content(); ?></a>
</div>
<?php endwhile; ?>
</div><!-- #mainbar -->
<?php get_sidebar(); ?>
</div><!-- .container -->
</div><!-- #content-bottom -->
<?php get_footer(); ?>
Don't know how to add pagination, it is out of my comprehension.