Serialize xml with different ElementName to same object with VB.net or C#

Use models which implement the same interface. The specific model can specify the xml element name corresponding to the language:

<XmlRoot("Persona")> _
Public Class Person_Es
    Implements IXMLPerson
    <XmlElement("Edad")> _
    Public Property Age As Long Implements IXMLPerson.Age
    <XmlElement("Nombre")> _
    Public Property Name As String Implements IXMLPerson.Name
    Public Sub New()
    End Sub
End Class

<XmlRoot("Person")> _
Public Class Person_En
    Implements IXMLPerson
    <XmlElement("Age")> _
    Public Property Age As Long Implements IXMLPerson.Age
    <XmlElement("Name")> _
    Public Property Name As String Implements IXMLPerson.Name
    Public Sub New()
    End Sub
End Class

Public Interface IXMLPerson
    Property Name As String
    Property Age As Long
End Interface

And to load the xml into memory, only the correct language will serialize, so I used nested Try. If you have many languages, you would want to architect it a little better as to reduce and reuse code. This works for english and spanish:

Dim filename As String = "<your file name here>"
Dim myPerson As IXMLPerson = Nothing
Try
    Dim serializer As New XmlSerializer(GetType(Person_Es))
    Using sr As New StreamReader(filename)
        myPerson = CType(serializer.Deserialize(sr), Person_Es)
    End Using
Catch ex1 As Exception
    Try
        Dim serializer As New XmlSerializer(GetType(Person_En))
        Using sr As New StreamReader(filename)
            myPerson = CType(serializer.Deserialize(sr), Person_En)
        End Using
    Catch ex As Exception
        MessageBox.Show("Exception: " & ex.Message)
    End Try
End Try