You can do it like this. The forms will be different from yours because I coded it up as an example. Basically I have added a public method that allows another class to call PerformClick on its button. I believe that's what you were asking for.
' Form1 has two buttons, one for showing the Form2 object and another for performing the click on Form2.Button1
Public Class Form1
Private form2 As Form2
Private Sub ShowFormButton_Click(sender As System.Object, e As System.EventArgs) Handles ShowFormButton.Click
form2 = New Form2()
form2.Show()
End Sub
Private Sub PerformClickButton_Click(sender As System.Object, e As System.EventArgs) Handles PerformClickButton.Click
If form2 IsNot Nothing Then
form2.PerformClick()
End If
End Sub
End Class
' Form2 has a button and a textbox
Public Class Form2
Public Sub PerformClick()
Button1.PerformClick()
End Sub
Private Sub Button1_Click(sender As System.Object, e As System.EventArgs) Handles Button1.Click
TextBox1.Text &= "Clicked! "
End Sub
End Class