As Spidey mentioned... show some code. That said the process you describe is a bit long-winded.
The Letter part of the solution can be done by grabbing the first 3 characters of str using Left(str,3) this will bring in the leftmost 3 character (if there are less it will get what is there). Then check that you have 3 characters using str.Length(). If the length is less than 3 then append the appropriate number of 'X'.
The Numeric part can be done in a similar way. Your int is actually a string in your code above. If it was a real integer you can cast it to string. Use Right(int,5). Again check to see you have 5 digits and if not prepend with appropriate number of 0.
Have a go... if you run into problems post your code and someone is bound to help.
UPDATE
As there have been actual answers posted here is my solution
Function FormatMyString(str As String, num as String) As String
Dim result As String
result = Left(str,3).PadRight(3, "X"c).ToUpper() & Right(num,5).PadLeft(5, "0"c)
Return result
End Function
UPDATE 2
based on Wiktors answer... made an amendment to my solution to cope with different formats
Function FormatMyString(str As String, num as String, alpha as Integer, digits as Integer) As String
Dim result As String
result = Left(str, alpha).PadRight(alpha, "X"c).ToUpper() & Right(num, digits).PadLeft(digits, "0"c)
Return result
End Function
To use...
FormatMyString("ABCDE", "56",3 5) will return ABC00056
FormatMyString("ABCDE", "123456",4 3) will return ABCD456
FormatMyString("AB", "123456",4 3) will return ABXX456