Disclaimer - I work at Clustrix.
Magento solution architect and certified developer, Kevin Bortnick, recently gave a webinar entiteld "Scaling Techniques to Increase Magento Capacity" at Meet Magento NY. Kevin currently works for clustrix but prior to joining this year, he worked on large Magento sites such as The Home Depot and Dr. Jays. In the webinar he shares his practical experiences. He covers 3 front end strategies and 8 RDBMS scaling strategies including:
- Percona
- Faster hardware
- Master with read slaves
- Master/Master, Store/Admin
- True Multi-master
- Partitioning (Magento 2 feature CQRS)
- NoSQL
- ClustrixDB
I hope this webinar helps you find the right solution for your use case.