If you want to use your own logic to get it done, then here is the way.
Just append [:3] at the end of first statement to slice the list.
>>> sign, m, n = input().split()[:3]
+ 2 3 ? 1 20
>>>
>>> [sign,m,n] = [str(sign), int(m), int(n)]
>>>
>>> sign
'+'
>>>
>>> m
2
>>>
>>> n
3
>>>
And here is another way to accomplish the same in a single line.
For this you can use the concept of list comprehension.
>>> sign, m, n = [c if i == 0 else int(c) for i, c in enumerate(input().split()[:3])]
+ 2 3 ? 1 20
>>>
>>> sign
'+'
>>> m
2
>>> n
3
>>>
sign, m, n = [c if i == 0 else int(c) for i, c in enumerate(input().split()[:3])].